Yay. Fanart. But this one tickles me. It should have been done a long time ago. I'd totally play as the loveable rascal Slimer in Splatoon.
I don't dare say this would make either franchise better; the first Ghostbusters movie is probably my favorite movie of all time (and I'll go on record saying that -- it's a brilliant comedy). And Splatoon scratches every competitive itch in my body just as well as Mario Kart does.
...Still, this would be fantastic.